Propofol
Propofol, yamamazwa nka Diprivan, mu yandi mazina, ni umuti ukora vuba utuma umuntu agabanuka mu bwenge ndetse no kubura kwibuka ibyabaye . Imikoreshereze yayo irimo gutangiza no kubungabunga uburyo bwo gusinziriza indwara rusange, gusinziriza abantu bakuru bafite umwuka uhagije, no gusinziriza indwara.[1] Ikoreshwa kandi ku ndwara ya status epilepticus iyo indi miti itarakora.[1] Itangwa binyuze mu gutera mu mitsi, kandi ingaruka ntarengwa zigera ku minota ibiri kugira ngo iboneke kandi akenshi imara iminota itanu kugeza ku icumi.[1]
Ingaruka mbi zikunze kugaragara za propofol zirimo umuvuduko w'umutima utari mwiza, umuvuduko w'amaraso uri hasi, kumva ubushyuhe aho umuntu atewe ndetse no guhagarika guhumeka . Izindi ngaruka mbi zishobora kuba zirimo gucika intege, kwandura indwara ziterwa no gukoresha nabi, kuba imbata, ndetse no kugira indwara ya propofol infusion syndrome iyo ikoreshejwe igihe kirekire.[1] Uyu muti usa nkaho ufite umutekano wo kuwukoresha mu gihe cyo gutwita ariko ntabwo wasuzumwe neza kugira ngo uwukoreshe muri iki kibazo.[1] Ntibyemewe gukoreshwa mu gihe cyo kubagwa.[1] Si umuti ugabanya ububabare, bityo imiti ya opioid nka morphine nayo ishobora gukoreshwa,[2] ariko niba ihora ikenewe cyangwa idakenewe ntibirasobanuka neza.[3] Bikekwa ko Propofol ikora nibura igice cyayo binyuze muri receptor ya GABA.[1]
Propofol yavumbuwe mu 1977 yemererwa gukoreshwa muri Leta Zunze Ubumwe za Amerika mu 1989.[4] Iri ku rutonde rw'imiti y'ingenzi y'Umuryango w'Abibumbye wita ku Buzima [5] kandi iraboneka nk'umuti rusange.[1] Igiciro cya buguzi mu bihugu biri mu nzira y'amajyambere kiri hagati ya 0.61 na 8.50 USD kuri buri kapu. Byitwaga amata ya amnesia (ikinamico ku ' mata ya magnesia '), bitewe n'uko ikoreshwa mu mitsi rimeze nk'amata.[6][7] Propofol ikoreshwa kandi mu buvuzi bw'amatungo mu gusinziriza.[8]
Iriburiro
[Hindura | hindura inkomoko]- 1 2 3 4 5 6 7 8 "Propofol". The American Society of Health-System Pharmacists. Archived from the original on 9 October 2016. Retrieved 21 January 2017. Archived 9 Ukwakira 2016 at the Wayback Machine
- ↑ Miner, JR; Burton, JH (August 2007). "Clinical practice advisory: Emergency department procedural sedation with propofol". Annals of Emergency Medicine. 50 (2): 182–7. doi:10.1016/j.annemergmed.2006.12.017. PMID 17321006.
- ↑ Wakai, A; Blackburn, C; McCabe, A; Reece, E; O'Connor, G; Glasheen, J; Staunton, P; Cronin, J; Sampson, C; McCoy, SC; O'Sullivan, R; Cummins, F (29 July 2015). "The use of propofol for procedural sedation in emergency departments". The Cochrane Database of Systematic Reviews. 7 (7): CD007399. doi:10.1002/14651858.CD007399.pub2. PMC 6517206. PMID 26222247.
- ↑ Miller's Anesthesia (8 ed.). Elsevier Health Sciences. 2014. p. 920. ISBN 9780323280112.
- ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ↑ Euliano TY, JS (2004). "A brief pharmacology related to anesthesia". Essential anesthesia: from science to practice. Cambridge, UK: Cambridge University Press. p. 173. ISBN 978-0-521-53600-4. Retrieved 2 June 2009.
- ↑ MD, David M. Novick (2017). A Gastroenterologist's Guide to Gut Health: Everything You Need to Know About Colonoscopy, Digestive Diseases, and Healthy Eating. Rowman & Littlefield. p. 15. ISBN 9781442271999.
- ↑ "Anesthesia Medications". Veterinary Dentistry for the Small Animal Technician. Hoboken: Wiley. 2013. ISBN 9781118694800.