RBFOX1

RBFOX1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ERR, 4ZKA, 2N82
Dynodwyr
Cyfenwau	RBFOX1, 2BP1, A2BP1, FOX-1, FOX1, HRNBP1, RNA binding protein, fox-1 homolog 1, RNA binding fox-1 homolog 1
Dynodwyr allanol	OMIM: 605104 HomoloGene: 69339 GeneCards: RBFOX1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • mRNA binding • RNA binding • nucleic acid binding Cydrannau o'r gell • cytoplasm • trans-Golgi network • cnewyllyn cell Prosesau biolegol • regulation of RNA splicing • mRNA processing • regulation of alternative mRNA splicing, via spliceosome • RNA splicing • nervous system development • RNA transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	54715	n/a
Ensembl	ENSG00000078328	n/a
UniProt	Q9NWB1	n/a
RefSeq (mRNA)	NM_001142333 NM_001142334 NM_001308117 NM_018723 NM_145891 NM_145892 NM_145893 NM_001364800	n/a
RefSeq (protein)	NP_001135805 NP_001135806 NP_001295046 NP_061193 NP_665898 NP_665899 NP_665900 NP_001351729	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RBFOX1 yw RBFOX1 a elwir hefyd yn RNA-binding protein fox-1 homolog 1 a Fox-1-like RNA-binding protein 1 isoform D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBFOX1.

• "Extending the phenotypic spectrum of RBFOX1 deletions: Sporadic focal epilepsy. ". Epilepsia. 2015. PMID 26174448.
• "A2BP1 gene polymorphisms association with olanzapine-induced weight gain. ". Pharmacol Res. 2015. PMID 26092620.
• "Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition. ". Nucleic Acids Res. 2017. PMID 28505313.
• "Rare variants in fox-1 homolog A (RBFOX1) are associated with lower blood pressure. ". PLoS Genet. 2017. PMID 28346479.
• "Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression.". PLoS One. 2015. PMID 26274327.